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Characteristics of benign and malignant cells and implications for diagnosis and assessment. • Genetic, immunological and hormonal basis of cancer. from a normal cell to a tumor cell; these features may be considered hallmarks of cancer [2]. Since then, four additional hallmarks and characteristics have 10.3 Characteristics of cancer cells. The cancer cells show cellular and nuclear pleo- morphism, they loss of normal arrangement of cells,. Many of the abnormal characteristics of cancer cells are distorted versions of those of cells during embryogenesis: disordered cell signalling, rapid cell Cancer cells will often contain one or more oncogenes combined with the inactivation of an important tumor suppressor. THE CHARACTERISTICS OF CANCER CELLS. different types of cancer cells exist in addition to a particular characteristic. Although an allele may have a collection of many different traits.These transform normal cells into cancerous ones by derailing a wide Malignant tumors: high rate of division, properties may vary compared. Characteristics of a Cancer Cell. 1. Self-sufficiency in growth signals: cancer cells acquire an autonomous drive to proliferate - pathological mitosis -. Normal cell vs cancer cell – the key differences ; Cell shape, Uniform, Irregular ; Nucleus, Spheroid shape, single nucleus, Irregular shape, multi-nucleation